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Uma estratégia inicial para o manejo da hipertensão era alterar o equilíbrio do Na+ pela restrição de sal na dieta. A alteração farmacológica do equilíbrio de Na+ foi possível com o desenvolvimento de diuréticos tiazídicos ativos por via oral. Assinale a alternativa CORRETA que corresponde a um dos diuréticos poupadores de K+.
Com base nos tipos de dor e características da dor, assinale a alternativa CORRETA que corresponde ao tipo de dor superficial, em queimação, sensação de frio doloroso, choque, formigamento, amortecimento, coceira, alfinetada e agulhada.
The selection of medications is one of the most important activities in pharmaceutical care. One of the technical criteria to be considered is:
Nausea and vomiting can be manifestations of a wide variety of conditions. Regarding 5-HT3 serotonin receptor antagonists, it is correct to say:
The pharmacokinetics of a drug involve its passage through various cellular membranes. Understanding the transport mechanisms and the physicochemical properties of molecules and membranes is essential to comprehend the distribution of drugs in the human body. Regarding the passage of drugs through membrane barriers, judge the following statements as true (T) or false (F):

(__)The plasma membrane is fluid and flexible, due to the presence of microdomains, such as "lipid rafts," and is organized with proteins that function as structural anchors, receptors, ion channels, and transporters.
(__)The Na+/K+-ATPase pump is an important example of facilitated diffusion, which is one of the therapeutic targets of digoxin used in the treatment of heart failure.
(__)In passive transport, the drug moves by diffusion following a concentration gradient, depending on its solubility in the lipid bilayer, the concentration gradient, the partition coefficient, and the membrane area.

Select the alternative in which the respective order of judgment is correct: